Yearly Archives: 2013
NSI-566 to be tested in patients with chronic spinal cord injury
ROCKVILLE, Md., Jan. 14, 2013 /PRNewswire/ — Neuralstem, Inc. (NYSE MKT: CUR) announced that it received approval from the United States Food and Drug Administration (FDA) to commence a Phase I safety trial of its lead cell therapy candidate, NSI-566, in chronic spinal cord injury patients. This open-label, multi-site study, will enroll up to eight patients with thoracic spinal cord injuries (T2-T12), who have an American Spinal Injury Association (AIS) A level of impairment, between one and two years after injury. AIS A impairment refers to a patient with no motor or sensory function in the relevant segments at and below the injury, and is considered to be complete paralysis.
CASA GRANDE, Arizona — A Casa Grande man who is a former U.S. Border Patrol agent created and patented a video game controller for people with severe spinal cord injuries.
Luis Pena formed LP Accessible Technologies and created the controller out of necessity. He was injured in an auto accident on the job in 2007 and is a quadriplegic.
His company focuses on building video game controllers that disabled people can use to play video games.
A longtime video game buff, Pena missed playing games after he recovered from the accident. So, he set out to create a controller he, and other people with disabilities, could use.
COLUMBUS, Ohio – An experimental oral drug given to mice after a spinal cord injury was effective at improving limb movement after the injury, a new study shows.
The compound efficiently crossed the blood-brain barrier, did not increase pain and showed no toxic effects to the animals.
“This is a first to have a drug that can be taken orally to produce functional improvement with no toxicity in a rodent model,” said Sung Ok Yoon, associate professor of molecular & cellular biochemistry at Ohio State University and lead author of the study. “So far, in the spinal cord injury field with rodent models, effective treatments have included more than one therapy, often involving invasive means. Here, with a single agent, we were able to obtain functional improvement.”
In 2007, an ATV accident left military veteran Scott Williams with a spinal cord injury that paralyzed him from the upper chest down. In the summer of 2012, after undergoing an autologous adipose-derived stem cell transplant into his spine at the Precision StemCell facility in Gulf Shores, Williams began noticing increased sensation in his left leg and the ability to slightly move both feet.
“Within one month, I was able to move my feet some, and I haven’t done that in over five years,” Williams stated.
LP Accessible Technologies was founded by Luis Pena. Luis became a quadriplegic on October 18, 2007 when he was involved in a rollover accident while working. Living with the injury inspired him to build a product and provide it to others that would allow them to game again; as he did prior to the accident. The LP Pad was invented as a result to his determination to be more independent and desire to socialize with the world.