Wednesday, February 26, 2020

Tag: Glial Growth

Do Zebrafish Hold an Ingredient to Heal Spinal Cord Injuries?

Published: November 2, 2016

do-zebrafish-heal-spinal-cord-injuriesResearchers have identified a protein in zebrafish that plays a role in helping heal major spinal cord injuries. The results, published in the 4 November issue of Science, could provide an important clue for researchers looking for ways to facilitate similar tissue repair in humans.

While mammals lack the ability to regenerate nervous system tissue after spinal cord injury, zebrafish can regenerate such tissue. The mechanisms behind this recovery have remained elusive.

“Only six to eight weeks after a paralyzing injury that completely severs their spinal cord, zebrafish form new neurons, regrow axons and recover the ability to swim. Importantly, these regenerative events proceed without massive scarring,” explained Mayssa Mokalled of Duke University, a researcher involved in the study.

Scientists discover trigger for protective immune response to spinal cord injuries

Published: February 5, 2015

Hot on the heels of discovering a protective form of immune response to spinal cord injury, researchers at the University of Virginia School of Medicine have pinpointed the biological trigger for that response – a vital step toward being able to harness the body’s defenses to improve treatment for spine injuries, brain trauma, Alzheimer’s disease and other neurodegenerative conditions.

Acorda Wins $2.67M Army Contract for Spinal Cord Injury Drug Trial

Published: January 24, 2013

Acorda Therapeutics said today it won a $2.67 million contract from the U.S. Army Medical Research and Material Command (USAMRMC) to support development of AC105 as a treatment for acute spinal cord injury (SCI).

The contract will help fund a Phase II clinical trial designed primarily to assess the safety and tolerability of AC105 in patients with acute SCI. The company plans to open enrollment for this study in the first half of this year.

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