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Articles Tagged: Study

Half of spinal cord injury patients may still have some connectivity, Australian study finds

Published: January 31, 2018 | Category: News | Spinal Cord Injury: ,

The sensation James Stanley misses most is the squidgey feeling of wet sand between his toes. Sometimes it’s dangling his legs into cool water, and the feeling of soft grass under his feet.

“They’re very simple things, but when you haven’t felt them for seven years I just think it would be amazing to feel them again,” the 25-year-old said.

A rare surfing injury called surfer’s myelopathy paralysed Mr Stanley from the navel down when he was 19 years old. As he pushed up on his surfboard his spine hyper-extended, triggering a swelling and spinal cord blockage at his T10 vertebra. Continue Reading »

People with tetraplegia gain rapid use of brain-computer interface

Published: January 24, 2018 | Category: News

For a brain-computer interface (BCI) to be truly useful for a person with tetraplegia, it should be ready whenever it’s needed, with minimal expert intervention, including the very first time it’s used. In a new study in the Journal of Neural Engineering, researchers in the BrainGate collaboration demonstrate new techniques that allowed three participants to achieve peak BCI performance within three minutes of engaging in an easy, one-step process.

One participant, “T5,” a 63-year-old man who had never used a BCI before, needed only 37 seconds of calibration time before he could control a computer cursor to reach targets on a screen, just by imagining using his hand to move a joystick. Continue Reading »

Spinal cord injury affects the heart

Published: December 13, 2017 | Category: News

Spinal cord injury affects the heart, that’s what research published in Experimental Physiology and carried out by researchers from University of British Columbia, Canada has found.

The heart undergoes changes after spinal cord injury that are dependent on how severe the spinal cord injury is but only a small amount of “sparing” (i.e., a small number of nerve fibers preserved) in the spinal cord are necessary for the heart to function at a near normal level. Continue Reading »

Scientists discover new way to help nerve regeneration in spinal cord injury

Published: December 11, 2017 | Category: News

There is currently no cure for spinal cord injury or treatment to help nerve regeneration so therapies offering intervention are limited. People with severe spinal cord injuries can remain paralysed for life and this is often accompanied by incontinence.

A team led by Drs Liang-Fong Wong and Nicolas Granger from Bristol’s Faculty of Health Sciences has successfully transplanted genetically modified cells that secrete a treatment molecule shown to be effective at removing the scar following spinal cord damage. The scar in the damaged spinal cord typically limits recovery by blocking nerve regrowth. Continue Reading »

New Neural Network Can Restore Diaphragm Function after Spinal Cord Injury

Published: October 17, 2017 | Category: News | Spinal Cord Injury:

Bottom Line: A team of neuroscientists has uncovered a neural network that can restore diaphragm function after spinal cord injury. The network allows the diaphragm to contract without input from the brain, which could help paralyzed spinal cord injury patients breathe without a respirator.

Journal in Which the Study was Published: Cell Reports

Author: Jared Cregg, Neurosciences graduate student at Case Western Reserve University School of Medicine in Cleveland, Ohio is first author on the study. Continue Reading »

New functional scoring helps better treatment for SCI during hESC

Published: October 6, 2017 | Category: News

During the past 2 decades, cell-based therapies for SCI have been researched in several studies. Replacement of damaged neural tissues and re-establishing connections between the central and peripheral nervous system is vital for the treatment strategy for patients with SCI. According to factsheet of WHO, over 5 hundred thousand people are estimated to suffer from SCI per year. American Spinal Injury Association’s (ASIA) Impairment Scale is a universally accepted scale to assess the SCI, but this scale does not cover all parameters of SCI. Development of new scoring system by Nutech mediworld has the remaining parameters covered in its Nutech Functional score(NFS). Continue Reading »

Researchers Turn Skin Cells into Motor Neurons Without Using Stem Cells

Published: September 7, 2017 | Category: News

Cellular Renovation

Why build something from the ground up when one can just renovate an already existing structure? Essentially, that’s what researchers from the University of Washington School of Medicine in St. Louis had in mind when they developed a method for transforming adult human skin cells into motor neurons in a lab. They published their work in the journal Cell Stem Cell. Continue Reading »

Nanoparticles limit damage in spinal cord injury

Published: September 5, 2017 | Category: News

Injection after an injury reduces inflammation and scarring

After a spinal cord injury, a significant amount of secondary nerve damage is caused by inflammation and internal scarring that inhibits the ability of the nervous system to repair itself.

A biodegradable nanoparticle injected after a spinal cord trauma prevented the inflammation and internal scarring that inhibits the repair process, reports a new Northwestern Medicine study. Continue Reading »

Exercise Improves Fitness and Strength for Adults with Spinal Cord Injury

Published: August 3, 2017 | Category: Information

Exercise is particularly beneficial for adults with chronic spinal cord injuries, says a review published by NeurologyNow.

Does Exercise Help?

People with spinal cord injuries are far less active compared to people in the general population and even compared to people with other disabilities.

That’s why researchers in the United Kingdom and Canada decided to review the available evidence to see how much and what types of exercise are beneficial for people with these types of injuries. Continue Reading »

Asterias Biotherapeutics Receives FDA Clearance to Enroll C-4 Patients in SCiStar Study

Published: July 10, 2017 | Category: News | Spinal Cord Injury:

Ability to enroll patients with second most common cervical spinal cord injury broadens eligible population for SCiStar study and future trials

FREMONT, Calif., July 10, 2017 /PRNewswire/ — Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company pioneering the field of regenerative medicine, today announced that the U.S. Food and Drug Administration (FDA) has accepted the company’s amendment to the clinical research protocol for its ongoing AST-OPC1 SCiStar Phase 1/2a clinical trial in motor complete cervical spinal cord injury (SCI). The amendment expands the eligibility criteria to include patients with a C-4 spinal cord injury and extends the dosing window from 14 to 30 days to 21 to 42 days post-injury. Continue Reading »