Recently researchers discovered an axon guidance protein known as Plexin B2 in the central nervous system (CNS). During the spinal cord injury, this protein plays a significant role in the healing of the wound and neural repair.
The experiment was designed and conducted by the Icahn School of Medicine at Mount Sinai. This study could help the development of the treatments or therapies which target axon guidance pathways for treating the patients of Spinal cord injury more effectively.
Permanent neurological impairments can occur after spinal cord injury (SCI) due to the failure of the spinal cord motor and sensory axons to regenerate.
This is because the mammalian central nervous system (CNS), unlike in some amphibians and reptiles, has inhibitory molecules blocking growth post-development, as well as the lack of an effective regenerative response system. Within the peripheral nervous system (PNS), there is some limited axonal recovery that can occur naturally.
Chronic pain is a common and often debilitating problem that can significantly impact function and quality of life for patients with spinal cord injury.
To help find treatment solutions, UBC researchers are investigating the effectiveness of a drug called Targin at treating chronic pain in individuals with spinal cord injury. The research team is now recruiting study participants.
Potential First-in-Class Therapy for Chronic Spinal Cord Injury
NEW HAVEN, Conn., Jan. 08, 2020 (GLOBE NEWSWIRE) — ReNetX Bio announced today that the U.S. Food and Drug Administration (FDA) has granted the company Fast Track Designation for ReNetX Bio’s clinical therapy (AXER-204) for the potential treatment of Chronic Spinal Cord Injury (SCI). ReNetX Bio is currently conducting a Phase 1/2 clinical trial “RESET” in patients with SCI, with topline results expected in 2021.
Columbia engineers invent a robotic trunk-support-trainer to retrain patients with spinal cord injury to sit more stably and gain an expanded active sitting workspace
A new study led by a University of Calgary researcher at the Cumming School of Medicine (CSM) finds that fatigue and sleep may need more attention in order to prevent issues like stroke after spinal cord injury.
“People with spinal cord injury have alarming rates of stroke, and we wanted to understand why,” says study lead Dr. Aaron Phillips, Ph.D., assistant professor, in the Department of Physiology & Pharmacology, and member of the CSM’s Libin Cardiovascular Institute of Alberta and the Hotchkiss Brain Institute.
Feinstein Institutes research examines new closed-loop neurostimulation
MANHASSET, NY — Researchers at The Feinstein Institutes for Medical Research used new closed-loop neurostimulation methods and textile-based electrodes to facilitate individual finger movement and grasp force regulation in quadriplegia individuals. Their results were published in the Springer Nature journal, Bioelectronic Medicine.
Acupuncture improves bladder function for spinal cord injury patients. First Affiliated Huai’an People’s Hospital of Nanjing Medical University researchers find acupuncture combined with intermittent catheterization alleviates neurogenic bladder dysfunction caused by traumatic spinal cord injuries . The study found significant improvements in bladder capacity, residual volume, urinary flow rate, urinary volume, and detrusor pressure following this combined treatment approach.
University of Louisville researchers are finding ways to help those who suffer catastrophic spinal cord injuries battle other health problems related to their injury.
UBC research shows personal input and collaboration provide positive results
New co-created research at UBC’s Okanagan campus has resulted in ground-breaking increases in physical activity and fitness for those living with spinal cord injury (SCI).