Wednesday, February 26, 2020

Tag: UC San Diego

New Injection Technique May Boost Spinal Cord Injury Repair Efforts

Published: January 29, 2020

In rodent studies, method reduced likelihood of further spinal cord trauma while delivering large doses of potentially reparative stem cells; the approach may have utility for multiple neurodegenerative conditions

Writing in the journal Stem Cells Translational Medicine, an international research team, led by physician-scientists at University of California San Diego School of Medicine, describe a new method for delivering neural precursor cells (NSCs) to spinal cord injuries in rats, reducing the risk of further injury and boosting the propagation of potentially reparative cells.

Created Line of Spinal Cord Neural Stem Cells Shows Diverse Promise

Published: August 6, 2018

Derived from human pluripotent stem cells, these diverse cells advance disease modeling and may provide new, scalable source of replacement cells for spinal cord injuries

Researchers at University of California San Diego School of Medicine report that they have successfully created spinal cord neural stem cells (NSCs) from human pluripotent stem cells (hPSCs) that differentiate into a diverse population of cells capable of dispersing throughout the spinal cord and can be maintained for long periods of time.

Stem Cell-Based Phase I Trial to Repair Spinal Cord Injuries Produces Encouraging Results

Published: June 1, 2018 | Spinal Cord Injury: , , , , , , , , , ,

First-in-human clinical study found improved motor and sensory function in three of four participants

Writing in the June 1 issue of Cell Stem Cell, researchers at University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord injuries produced measurable improvement in three of four subjects, with no serious adverse effects.

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