Tag: Nature Methods
Derived from human pluripotent stem cells, these diverse cells advance disease modeling and may provide new, scalable source of replacement cells for spinal cord injuries
Researchers at University of California San Diego School of Medicine report that they have successfully created spinal cord neural stem cells (NSCs) from human pluripotent stem cells (hPSCs) that differentiate into a diverse population of cells capable of dispersing throughout the spinal cord and can be maintained for long periods of time.
A recent study shows embryonic stem cells and human induced pluripotent stem (IPS) cells are virtually identical. Human IPS cells were first produced in 2006 from mouse cells and in 2007 from human cells. Since then, scientists believed human IPS cells were equivalent to embryonic stem cells.
“In this study, we applied very cutting edge proteomic technologies to look at all the proteins or a very large percentage of them (in both types of cells) and we compared many cell lines, and what we found was that the protein levels are very similar in the two cell types,” said lead researcher Josh Coon, an associate professor of chemistry and biomolecular chemistry at the University of Wisconsin-Madison, as quoted by Medical News Today.