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Articles Tagged: Stem Cells

Adult Stem Cells Treat Spinal Cord Injury

Published: February 5, 2018 | Category: News | Spinal Cord Injury: ,

Laura Dominguez-Tauer is a living, breathing example of what it takes to overcome adversity. An oil spill on a San Antonio freeway is blamed for the car crash that sent Laura and her brother directly into a retaining wall in 2001. As she lay tangled in the middle of the car, she heard a paramedic say, “get a neck brace, she has a broken neck.”

“I didn’t feel anything. I couldn’t move my arms, I couldn’t move my hands,”

Laura was paralyzed from the neck down. “I didn’t feel anything. I couldn’t move my arms, I couldn’t move my hands,” Laura said. Continue Reading »

Central Michigan University graduate student conducts research for spinal cord injuries

Published: December 3, 2017 | Category: News

Hartland graduate student Andrew Stewart has dedicated nearly five years of his life to finding a cure for spinal cord injuries.

Stewart chose spinal cord injury research in 2009 after his brother was involved in an accident that damaged his spinal cord and left him paralyzed in a wheelchair.

“He had fallen from a third-story balcony onto a concrete slab,” Stewart said. “That’s what moved me to pursue a career in research to find a cure for spinal cord injuries.” Continue Reading »

Using donor stem cells to treat spinal cord injury

Published: August 28, 2017 | Category: News

Immune cells populating spinal cord after injury affect ability of stem cells to promote recovery

A new study in mice published in The Journal of Neuroscience details a potential therapeutic strategy that uses stem cells to promote recovery of motor activity after spinal cord injury.

The transplantation of neural stem cells could help promote repair of an injured spinal cord, but the interaction between donor cells and the resident cells that are part of the body’s immune response to injury is not well understood. Continue Reading »

It’s Not a Rat’s Race for Human Stem Cells Grafted to Repair Spinal Cord Injuries

Published: August 28, 2017 | Category: News

Lengthy study finds that implanted neural stem cells grow slow and steady, and success needs to be measured accordingly

More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year after grafting. Continue Reading »

A Year Ago He Was Paralyzed From the Neck Down — Then This Happened

Published: August 24, 2017 | Category: News | Spinal Cord Injury: , , ,

You might feel a bit down if you watch the news. Who wouldn’t?

Angry people might be grabbing headlines and making you wonder about the future, but the antidote is all around you.

Talk to some of your neighbors. Chances are, no matter what they look like or where they’re originally from, you’ll find they’re actually pretty decent people — just like you.

The little improvements we all try to make may not register much, but the accumulation of them all eventually does. Continue Reading »

Asterias Biotherapeutics Receives FDA Clearance to Enroll C-4 Patients in SCiStar Study

Published: July 10, 2017 | Category: News | Spinal Cord Injury:

Ability to enroll patients with second most common cervical spinal cord injury broadens eligible population for SCiStar study and future trials

FREMONT, Calif., July 10, 2017 /PRNewswire/ — Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company pioneering the field of regenerative medicine, today announced that the U.S. Food and Drug Administration (FDA) has accepted the company’s amendment to the clinical research protocol for its ongoing AST-OPC1 SCiStar Phase 1/2a clinical trial in motor complete cervical spinal cord injury (SCI). The amendment expands the eligibility criteria to include patients with a C-4 spinal cord injury and extends the dosing window from 14 to 30 days to 21 to 42 days post-injury. Continue Reading »

Lab-Grown Neurons Could Help Heal Spinal Injuries and Restore Movement

Published: April 26, 2017 | Category: Featured News Videos

Researchers grew human spinal cord neurons from stem cells and injected them into healthy mice, where they successfully connected with other neurons. Continue Reading »

The future of stem cells: tackling hype versus hope

Published: January 28, 2017 | Category: News

Professor Alan Mackay-SimControversy surrounds the link between Australian of the Year Alan Mackay Sim’s research and a Polish team who restored mobility for a paraplegic man.

For many people suffering from disabling conditions, such as Parkinson’s disease, spinal injury and paralysis, multiple sclerosis, macular degeneration, heart disease, renal failure and even cancer, announcements in the press around breakthroughs in stem cell research undoubtedly bring hope.

The challenge remains how to accurately communicate what is genuinely possible in terms of therapies and what we scientists hope might be possible but do not yet have strong evidence for. Continue Reading »

Generating improvement in spinal cord injuries

Published: January 24, 2017 | Category: News

Early clinical trial results announced offer new hope in regenerative medicine

A new therapy to treat spinal cord injuries in people who have lost all motor and sensory function below the injury site shows additional motor function improvement at 6-months and 9-months following treatment with 10 million AST-OPC1. The positive efficacy results from an ongoing research study were announced on Jan. 24 in a conference held by Asterias Biotherapeutics, Inc., the biotechnology company that manufactures AST-OPC1. Continue Reading »

What are stem cells and how will they be used to treat the world’s most debilitating diseases?

Published: January 12, 2017 | Category: Answers

Stem cell research is often controversial but it has also led to incredible medical progress in recent years.

Stem cell research is at defining moment. Although it can be controversial and does raise a lot of important ethical issues, this area of medical science has been characterised by a number of important advances, ever since the first embryonic stem cells were isolated from mice in the 1980s. In the near future, it could reshape the way we treat some of the world’s most debilitating diseases.

Stem cells have already been used as treatment for a number of years – think bone marrow transplant – and they have the potential to help with many other medical conditions. Continue Reading »