Tuesday, August 20, 2019

Tag: University of Michigan

Nanoparticles promote functional healing following spinal cord injury

Published: July 24, 2019

Novel approach also shows promise for autoimmune diseases

Paralyzing damage in spinal cord injury (SCI) is often caused by the zealous immune response to the injury. NIBIB-funded engineers have developed nanoparticles that lure immune cells away from the spinal cord, allowing regeneration that restored spinal cord function in mice.

An ‘EpiPen’ for spinal cord injuries

Published: July 11, 2019

ANN ARBOR—An injection of nanoparticles can prevent the body’s immune system from overreacting to trauma, potentially preventing some spinal cord injuries from resulting in paralysis.

The approach was demonstrated in mice at the University of Michigan, with the nanoparticles enhancing healing by reprogramming the aggressive immune cells—call it an “EpiPen” for trauma to the central nervous system, which includes the brain and spinal cord.

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