Saturday, March 6, 2021

Tag: Embryonic Stem Cell Research

New functional scoring helps better treatment for SCI during hESC

Published: October 6, 2017

During the past 2 decades, cell-based therapies for SCI have been researched in several studies. Replacement of damaged neural tissues and re-establishing connections between the central and peripheral nervous system is vital for the treatment strategy for patients with SCI. According to factsheet of WHO, over 5 hundred thousand people are estimated to suffer from SCI per year. American Spinal Injury Association’s (ASIA) Impairment Scale is a universally accepted scale to assess the SCI, but this scale does not cover all parameters of SCI. Development of new scoring system by Nutech mediworld has the remaining parameters covered in its Nutech Functional score(NFS).

Spinal Cord Injury Whiteboard Video

Published: February 17, 2017

Stem cell research for spinal cord injury

Published: December 10, 2015

Spinal cord injury (SCI) involves damage to the area that can cause an impairment of loss of muscle control, movement and sensation.  Currently, patients with injury to the spinal cord are managed with physical therapy, occupation therapy and other rehabilitation methods to cope with the physical changes.

However, stem cell research may present a new approach to the management of this patient group, allowing for a potential improvement in the symptoms of the condition, such as incontinence, muscular control and sexual function.

StemCells Inc says spinal injury therapy shows promise

Published: November 19, 2015

experimental stem cell therapyStemCells Inc said its experimental stem cell therapy improved the functioning and strength of limbs in patients with spinal cord injuries, becoming the second company to report promising data on the treatment for such injuries.

StemCells Inc said its experimental stem cell therapy improved the functioning and strength of limbs in patients with spinal cord injuries, becoming the second company to report promising data on the treatment for such injuries.

Australian treated with new cell-based therapy

Published: June 1, 2015

In a rare surgery, a 35-year-old Australian woman with a spinal injury for 14 long years regained her sensory ability after undergoing a new cell-based therapy at a hospital here, doctors said on Monday.

The Human Embryonic Stem Cell (HESC) also proved beneficial for Perry Gross as she gained back her standing capability, which she had lost after suffering a major trauma while playing rugby.

Critical Mass of Stem Cells Sets Off Embryonic Development in the Lab

Published: November 5, 2014

UCambridge Early Stage EmbryoWhen stem cells are propagated in the laboratory, they typically differentiate into one or another specialized cell type, usually forming cell masses that show little organization or spatial coherence. Exceptions include the emergence, in culture, of retinal and anterior cortex-like tissues. For the most part, however, stem cell aggregates in the laboratory prefer to remain lumps.

Despite coaxing, they refuse to organize themselves into structures that resemble embryos. In particular, they avoid taking the earliest steps of embryonic development—axis formation and gastrulation, the organized movement of cells that, using the initial axis as a reference, positions the head and the tail, the front and the back.

Stem cells from human embryos prove safe, improve vision -study

Published: October 14, 2014

(Reuters) – The longest-running trial of stem cells derived from a human embryo found that the cells caused patients none of the problems scientists feared, such as forming tumors, and reversed partial blindness in about half the eyes receiving transplants, researchers reported on Tuesday.

Stem cell trial for spinal cord injuries cleared by FDA

Published: August 27, 2014

michael-west-asteriasAn experimental treatment using controversial embryonic stem cells to fix severe spinal cord injuries has new life under a new company.

Asterias Biotherapeutics Inc. of Menlo Park received Food and Drug Administration clearance Wednesday to go forward with a 13-person safety study of so-called oligodendrocyte progenitor cells, or OPCs. Those cells, derived from embryonic stem cells, are thought to stimulate the growth of new nerve cells around the spinal cord and could help paralyzed patients regain movement.

Stem Cell Trials to Treat Spinal Cord Injuries

Published: June 5, 2014

Neuron-with-oligodendrocyte-and-myelin-sheathWhile human embryonic stem cells (hESCs) were originally created in 1998, it wasn’t until 2009 — over a decade later — that they were approved by the FDA for use in a clinical trial in people. It was a long wait, but the trial was quite the promising one. The clinical trial, undertaken by the Geron Corporation, was for using hESCs to treat patients with spinal cord injuries and paralysis.

Very unfortunately, the trial became stalled in late 2011, mostly due to financial concerns (but it did undoubtedly help pave the way for other hESC-based clinical trials to get FDA approval starting in 2010).

Stem Cell Agency Invests $32 Million Toward Therapies For Spinal Cord Injury and HIV/AIDS

Published: May 29, 2014

CIRMSan Diego, CA – A promising treatment for patients with spinal cord injuries and a therapy aimed at helping HIV patients create an AIDS-resistant blood system were approved today by the state’s stem cell agency, the California Institute for Regenerative Medicine (CIRM).

Both are part of the agency’s Strategic Partnership program, which aims to attract more industry investment in research projects funded by the stem cell agency, and accelerate the most promising projects into clinical trials. Both companies will match the funds that they are getting from the agency.