Tag: Spinal Cord Injury Research
(NAPSI)—If you or someone you care about is ever among the approximately 17,700 Americans who each year, according to The Journal of American Medical Association, suffer a new spinal cord injury or the hundreds of thousands that continue to live with a spinal cord injury, you may be relieved to learn about recent research.
A team of researchers from University of Toronto Engineering and the University of Michigan has redesigned and enhanced a natural enzyme that shows promise in promoting the regrowth of nerve tissue following injury.
Their new version is more stable than the protein that occurs in nature, and could lead to new treatments for reversing nerve damage caused by traumatic injury or stroke.
National Institutes of Health grant will enable Hedong Li to focus on role of micorRNAs in the reprogramming process
UNIVERSITY PARK, Pa. — Hedong Li, associate research professor of biology, has been awarded $1.8 million from the National Institutes of Health (NIH) to study how microRNAs — small segments of genetic material — could be used in treatments for spinal cord injury. The five-year grant builds upon previous work by Li and colleagues to convert glial cells, support cells that surround neurons, into functioning neurons.
Two top scientists at the University of Virginia School of Medicine are seeking answers to questions about spinal cord injuries that have long frustrated the development of effective treatments.
The scientists, Jonathan Kipnis, PhD, and Kodi Ravichandran, PhD, are teaming up to understand why critical nerve cells called neurons continue to die after spinal cord injuries. So little is known that doctors aren’t even certain if the body’s immune response is beneficial or harmful.
In experiments on rats with spinal cord injuries, the rodents improved their walking ability following treatment.
Researchers have demonstrated a novel method that might regrow nerve cells at the site of spinal injuries.
Recently researchers discovered an axon guidance protein known as Plexin B2 in the central nervous system (CNS). During the spinal cord injury, this protein plays a significant role in the healing of the wound and neural repair.
The experiment was designed and conducted by the Icahn School of Medicine at Mount Sinai. This study could help the development of the treatments or therapies which target axon guidance pathways for treating the patients of Spinal cord injury more effectively.
Here are six key updates in the treatment of spinal cord injuries in the past six months:
The Tim and Caroline Reynolds Center for Spinal Stimulation at Kessler Foundation opened in East Hanover, N.J., in January. The facility has more than 50 researchers focusing on spinal stimulation research and restoring function in people with paralysis. Gail Forrest, PhD, who specializes in applying electrical stimulation to spinal cord injury research, was appointed director of the center.
Permanent neurological impairments can occur after spinal cord injury (SCI) due to the failure of the spinal cord motor and sensory axons to regenerate.
This is because the mammalian central nervous system (CNS), unlike in some amphibians and reptiles, has inhibitory molecules blocking growth post-development, as well as the lack of an effective regenerative response system. Within the peripheral nervous system (PNS), there is some limited axonal recovery that can occur naturally.
Spinal cord injuries caused by accidents, violence and disease paralyze from the neck down more than 5,000 people every year. In the first few months after injury, some people regain some movement and sensation in their limbs. Those who do not show improvement in the first few months are unlikely to ever recover.