Tag: Nervous System
BACKGROUND: A new surgery is helping patients who have suffered a spinal cord injury or were born with spina bifida regain control of their bladder and bowel function.
Spina bifida is a serious birth defect that occurs when the tissue around the spinal cord doesn”t close properly. The spinal cord pushes through the opening, damaging nerve ends. It affects two out of every 1,000 births.
After birth, surgeons close the opening but scar tissue is left behind, which can cause neurological problems. As kids grow, they must have a detethering procedure to trim away the scar tissue.
The regeneration capacity of axons within the central nervous system, of which the spinal cord is part, has until now been much debated. Axons can regenerate toward the muscles, whereas in the opposite direction inhibiting factors prevent regrowth toward the nerve centers. The observation made by Geneviève Rougon’s team at IBDML shows that the axons also regrow in the direction of the spinal cord within a short lapse of time after the injury. Moreover, this regrowth is encouraged by post-traumatic angiogenesis, in other words by the process of formation of new blood vessels in the damaged tissue.
“Stem cell research and regenerative medicine are in an extremely exciting phase right now. We are gaining knowledge very fast and many companies are being formed and are starting clinical trials in different areas,” says Dr Jonas Frisén.
As an example, a first-in-human study was just initiated for Parkinson’s disease patients with the drug product, sNN0031, from the Swedish company NeuroNova.
The damage from primary and secondary insults of spinal cord injury can result in various hemodynamic alterations. It is important to understand the presentation and time course of these changes, in addition to the management of each, to avoid further clinical deterioration and complications.
Traumatic spinal cord injury has an incidence of 10,000 cases per year with a prevalence of approximately 200,000 people in the United States.1 These numbers do not account for deaths in the field, which are estimated to occur in 16% to 30% of these cases. The patient demographics mirror that of the general trauma population with the average age around 30 years and a male predominance. Although motor vehicle collisions account for roughly half of all spinal cord injury cases, other events including assaults, falls, work-place injuries, and sporting accidents account for a large portion of the rest.2
The Sixth Annual National Neurosurgery Awareness Week (NNAW) kicks off this year on May 3 during the 77th Annual Meeting of the AANS in San Diego. Approximately 3,000 neurosurgical medical professionals will meet to further their continuing medical education in specialty areas including spine and peripheral nerves, as well as cerebrovascular, pain, pediatrics, stereotactic, trauma, tumor, and socioeconomic issues affecting the specialty.
Patient necessity in southeast US affects innovative center
SANFORD, FL – A promising new resource with a proven methodology of recovery is now available for spinal cord injury persons living throughout the southeastern United States. Step It Up Recovery Center, Inc. in Sanford, Florida is now accepting clients for an innovative, exercise-based program modeled after the successful Project Walk® Spinal Cord Injury Recovery program in Carlsbad, CA.
“Step It Up Recovery Center, Inc. has been established to help those living with a spinal cord injury (SCI) improve their daily living – and perhaps ultimately walk again – through a proven, specialized and comprehensive exercise-based program,”