Thursday, June 4, 2020

Tag: axon

Increasing Energy Supply in Injured Spinal Cord Nerves May Help Promote Axon Regrowth

Published: March 3, 2020

Scientists at the National Institutes of Health (NIH) and the Indiana University School of Medicine report that increasing energy supply within injured spinal cord nerves in mice could help promote axon regrowth and restore some motor functions. The study “Restoring cellular energetics promotes axon regeneration and functional recovery after spinal cord injury,” appears in Cell Metabolism.

Can an Active Lifestyle Improve Recovery After a Spinal Cord Injury?

Published: January 23, 2020

Permanent neurological impairments can occur after spinal cord injury (SCI) due to the failure of the spinal cord motor and sensory axons to regenerate.

This is because the mammalian central nervous system (CNS), unlike in some amphibians and reptiles, has inhibitory molecules blocking growth post-development, as well as the lack of an effective regenerative response system. Within the peripheral nervous system (PNS), there is some limited axonal recovery that can occur naturally.

Using a Mini-Scaffold to Help Treat Spinal Cord Injury

Published: February 28, 2017

Patients suffering from complete spinal cord injuries have little to no treatment options that provide meaningful improvement in patient outcomes.

Cambridge, Mass.-based InVivo Therapeutics is trying to change that. Co-founded in 2005 by MIT professor Robert Langer, and surgeon-scientists Joseph Vacanti, M.D., the company has developed a small, bioresorbable and biocompatible device called the Neuro-Spinal Scaffold, to help patients with complete thoracic spinal cord injuries regain some function.

Study says stem cell treatment can aid recovery of spinal injuries

Published: August 23, 2016

stem-cellStem Cell treatment or the Human Embryonic Stem Cells (HESC) is effective in the replacement of damaged neurons, re-establishment of lost axonal connections, and providing of neuro-protective factors to allow the healing and recovery of spinal cord injury, revealed a study.

Stem Cell treatment or the Human Embryonic Stem Cells (HESC) is effective in the replacement of damaged neurons, re-establishment of lost axonal connections, and providing of neuro-protective factors to allow the healing and recovery of spinal cord injury, revealed a study.

Scientists Connect Neurons in the Lab for the First Time

Published: February 9, 2016

Scientists Connect Neurons in the LabInjuries to the central nervous system — the brain and spinal cord — are particularly devastating because the body doesn’t regenerate neurons to repair connections between vital circuits and restore function. In other words, the damage is permanent or even fatal.

A variety of early studies in animals and humans indicate the field of neural regeneration research is advancing. A 20-year-old man in Naples, Florida recently enrolled in the first clinical trial to assess the ability of stem cells to repair spinal cord injuries. But, a team of scientists from McGill University in Montreal, Canada, are working an entirely different method to inject hope into an otherwise bleak prognosis.

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