Researchers at ReNetX Bio are hoping a new name, the potential for a new influx of cash on the horizon and a new chief executive officer are the winning combination needed to bring its lead drug candidate to market.
ReNetX Bio is looking to guide its drug candidate, Nogo Trap, through its first round of clinical trials. Company officials say Nogo Trap is designed to help patients with chronic spinal cord injury.
Treatment proven in lab to assist recovery and could be part of cure alongside other research, say experts.
Kiwi and Australian researchers have developed a protein-based drug that offers a potential breakthrough treatment for those with severe brain and spinal cord injuries.
University of Auckland researcher Dr Simon O’Carroll said the drug, which could be injected straight into the blood stream or taken as a pill soon after an injury, could reduce damage, scarring and improve recovery.
Now the dust has settled on an unforgettable day of running and inspiration, the numbers that lie behind the second Wings for Life World Run show how the event captured the world’s imagination.
Encouraged and supported by thousands of volunteers, athletes from all four corners of the globe came together on Sunday, not just to provide a true sporting spectacle but also a formidable demonstration of determination and fun.
And the figures are finally in…
Case Western Reserve Scientists Design Intracellular Sigma Peptide (ISP) to Promote Functional Recovery Following Spinal Cord Injury
Case Western Reserve scientists have developed a new chemical compound that shows extraordinary promise in restoring function lost to spinal cord injury. The compound, which the researchers dubbed intracellular sigma peptide (ISP), allowed paralyzed muscles to activate in more than 80 percent of the animals tested. The remarkable study, partly funded by the National Institutes of Health, appears in the December 3 edition of the journal Nature.
Modern science can offer a lot of things, but the search for a miracle cure to spinal cord injury is dangerous on many levels.
It’s understandable that someone who has just been given life changing news will meet it with disbelief and doubt.
Say, for example, you’re told that an accident has left you with a fractured spine. Maybe it was a car crash. Perhaps it was a simple mistake like diving into a shallow pool or falling off a bike.
There are lots of technical terms being used by the people looking after you, yet all you really hear them saying is; “…you’ll never walk again.”
Adventurer Mark Pollock joined us to explore the frontier research that is pointing towards a cure for spinal cord injury.
A systematic survey of the scientific literature shows that stem cell therapy can have a statistically significant impact on animal models of spinal cord injury, and points the way for future studies.
Spinal cord injuries are mostly caused by trauma, often incurred in road traffic or sporting incidents, often with devastating and irreversible consequences, and unfortunately having a relatively high prevalence (250,000 patients in the USA; 80% of cases are male). High-profile campaigners like the late actor Christopher Reeve, himself a victim of sports-related spinal cord injury, have placed high hopes in stem cell transplantation. But how likely is it to work?
Ever since my injury three years ago I have been determined to show the world that people with disabilities can be just as happy, independent and productive as those without disabilities. But is it possible that showing such positivity could mask our daily hardships to the point that the urgency for a cure is diminished?
Don’t get me wrong, it’s important that society knows that we are more able than most would imagine. But sometimes it feels like that is the only message we’re getting out. What about the desire for a cure?
In April 2007, Amanda left a prom after-party with a friend who had been drinking.
On the way home, the driver crashed into a ditch. Amanda’s spinal cord was injured, and she was paralyzed from the neck down.
She was hospitalized for five months and went through a grueling regimen of physical therapy each day. Amanda had to relearn how to feed herself, brush her teeth, get dressed and do many other simple, everyday tasks. She was told she would never walk again. Six years later Amanda is still in a wheelchair.
Reports of paralysed animals walking again can give unrealistic hopes to people with spinal injuries. What is more important is that they develop the skills and perspective to get on with their lives
A recent breakthrough in regenerative medicine saw paraplegic dogs regaining some function in their back legs: inevitably, the headlines talked of hope for human patients with spinal cord injury.
But the head of clinical psychology at the National Spinal Injuries Centre, Professor Paul Kennedy, argues that this kind of “magic bullet” reporting can be damaging to people who are coming to terms with a life-changing injury.